Over the last few decades, the biosciences have undergone a mathematical revolution, shifting from qualitative to quantitative approaches as experimental and computational techniques generate unprecedented amounts of data. This has enabled us to investigate the mysteries of "living processes" at a deeper level, with the goal of eventually basing them on first principles physical laws. By developing novel theoretical and computational concepts to analyze and interpret this wealth of information, we can unlock new insights and deepen our understanding of the complex processes underlying life.